Isoxazole-5-(4H)-one derivatives have garnered considerable attention owing to their wide range of pharmacological activities, such as anti-inflammatory, analgesic, antimicrobial, and antitumor properties. The multicomponent synthesis of 3,4-disubstituted-isoxazole-5-(4H)-ones has attracted significant interest in recent years due to its effectiveness and capability to produce various molecular libraries. This review presents a thorough summary of the recent advancements […]