Iranian Journal of Catalysis (IJC)An effective and mild oxidative aromatization of isoxazolines and 2-pyrazolines by trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxalane promoted by ammonium iodide in water/MeCNVolume 5 (2015)Issue 2, June 201520240203An effective and mild oxidative aromatization of isoxazolines and 2-pyrazolines by trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxalane promoted by ammonium iodide in water/MeCNENAkbarMobinikhalediDepartment of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, IranKavehKhosraviFaculty of Science, Department of Chemistry, Arak University, Arak 38156-8-8349, Iran.SamiraKazemiDepartment of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, IranJournal Article20240203Pyrazoles and isoxazoles are well-known important heterocyclic compounds that due to their participation in the structure of many drugs are very important. Pyrazoles and isoxzaloes can be prepared by oxidation of pyrazolines and isoxazolines respectively. In this work, trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxalane (DHPDMDO)/NH4I has been used as a new, powerful, nearly green, effective and inexpensive oxidant for oxidative aromatization of isoxazolines and 2-pyrazolines to corresponding isoxazoles and 2-pyrazoles in the presence of catalytic amount of acetic acid at room temperature in water/MeCN within short reaction time. All products obtained in high yields and good purity by aqueous work-up condition. More complex purification methods is not necessary in this methodology.Iranian Journal of Catalysis (IJC)Diethylenetriamine supported on cellulose as a biodegradable and recyclable basic heterogeneous catalyst for the synthesis of spirooxindole derivativesVolume 5 (2015)Issue 2, June 201520240203Diethylenetriamine supported on cellulose as a biodegradable and recyclable basic heterogeneous catalyst for the synthesis of spirooxindole derivativesENBatolZakerinasabDepartment of Chemistry, College of Sciences, University of Birjand, Birjand 97175-615, IranMohammadAli NasseriDepartment of Chemistry, Faculty of Science, University of Birjand, P. O. Box 97175-615, Birjand, Iran.AliAllahresaniDepartment of Chemistry, Faculty of Science, University of Birjand, P. O. Box 97175-615, Birjand, Iran.Journal Article20240203In the present study, the synthesis of diethylene triamine supported on cellulose biopolymer as a biodegradable solid basic heterogeneous catalyst was suggested. Then, the applicability of the synthesized catalyst cellulose bonded N-propyl diethylene triamine (CBPDETA) was tested for the synthesis of oxindole derivatives, an important class of potentially bioactive compounds. A various series of tetrahydrospiro-[chromene-indoline]-carbonitrile and dihydro-spiro[pyrano quinoline--indoline]-carbonitrile are obtained in water, an excellent solvent in terms of environmental impact, in high yield (78- 98%) from one-pot reaction procedure involving dicarbonyl/ 4-hydroxycoumarine , malononitrile and isatin compounds. The catalyst has been reused several times, without observable loss of activity and selectivity.Iranian Journal of Catalysis (IJC)A green protocol for synthesis of pyran annulated hetrocyclic systems using Na2SO4 as an efficient catalystVolume 5 (2015)Issue 2, June 201520240203A green protocol for synthesis of pyran annulated hetrocyclic systems using Na2SO4 as an efficient catalystENMalekTaher MaghsoodlouChemistry Department, Faculty of Science, University of Sistan and Baluchestan, Zahedan, IranAminMasoumniaDepartment of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, IranMirRasul MousaviDepartment of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, IranNourollahHazeriDepartment of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, IranJasemAboonajmiDepartment of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, IranSayyedMostafa Habibi-KhorasaniDepartment of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, IranShivaKiaeeDepartment of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, IranJournal Article20240203Na2SO4 as an inexpensive and effective catalyst has provided a green protocol for the synthesis of tetrahydrobenzo[b]pyran, pyrano[2,3-d]pyrimidinone and dihydropyrano[3,2c]chromene derivatives from the three-component domino reaction of aromatic aldehydes and malononitrile with 4-hydroxycoumarin/ dimedone/ barbituric acid in ethanol/water as a mixture of solvent that, this mixture entirely is green solvent. Products could simply be separated from the catalyst. Using neutral and mild conditions, short reaction time, environmentally benign procedure, high to excellent yields of the products and easy work-up without using column chromatography are the advantages of this method. By virtue of these advantages, sodium sulfate can be used as catalyst in the organic transformations.Iranian Journal of Catalysis (IJC)An efficient synthesis of 4-aryl-7-benzylidene-hexahydro-2H-cyclopenta[d] pyrimidin-2-ones/thiones catalyzed by p-dodecylbenzenesulfonic acidVolume 5 (2015)Issue 2, June 201520240203An efficient synthesis of 4-aryl-7-benzylidene-hexahydro-2H-cyclopenta[d] pyrimidin-2-ones/thiones catalyzed by p-dodecylbenzenesulfonic acidENKrishnamoorthyAswinResearch Department of Chemistry, C. Abdul Hakeem College, Melvisharam – 632 509, IndiaMajidGhashangDepartment of Chemistry, Najafabad Branch, Islamic Azad University, P.O. Box: 517; Najafabad, IranSheikMansoorC. Abdul Hakeem College
Bio active Organic Molecule Synthetic Unit, Research Department of Chemistry, Melvisharam - IndiaJournal Article20240203A new and efficient method has been developed for the synthesis of 4-aryl-7-benzylidene-1,3,4,5,6,7-hexahydro-2H-cyclopenta[d]pyrimidin-2-ones through Biginelli-like reaction of cyclopentanone, with urea/thiourea and aromatic aldehyde employing p-dodecylbenzenesulfonic acid (DBSA) as a recyclable catalyst under solvent-free condition. The recovered catalyst was recycled for further runs. The product formation takes place via a cross-aldol condensation of benzaldehyde with cyclopentanone in the presence of DBSA to produce benzylidene intermediate and subsequent Michael addition. The present approach offers the advantages of short reaction time, mild reaction conditions, high yields and convenient operation. All the products were obtained in good to excellent yields and the structures of the synthesized compounds were established by advanced spectroscopic data.Iranian Journal of Catalysis (IJC)Spotlight- Hydroxylamine-O-sulfonic acid: As a dual role reagentVolume 5 (2015)Issue 2, June 201520240203Spotlight- Hydroxylamine-O-sulfonic acid: As a dual role reagentENMeysamYarieFaculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, IranJournal Article20240203Meysam Yarie was born in 1987 in Malayer, Hamedan, Iran. He received his B.Sc. in Applied Chemistry (2010) from Malek-Ashtar University of Technology and M.Sc. in Organic Chemistry (2012) from Kurdistan University under the supervision of Dr. Kamal Amani. He is currently working towards his Ph.D. under the supervision of Professor Mohammad Ali Zolfigol. His research interest is catalysis, including the synthesis, characterization and applications of homogeneous and heterogeneous catalysis in organic synthesis.Iranian Journal of Catalysis (IJC)(Diacetoxyiodo)benzene (DIB) catalyzed green and efficient synthesis of biscoumarin derivatives in aqueous mediaVolume 5 (2015)Issue 2, June 201520240203(Diacetoxyiodo)benzene (DIB) catalyzed green and efficient synthesis of biscoumarin derivatives in aqueous mediaENAmitWaghmarePost Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, Dist. Ahmednagar-413713 (MS), India0000-0003-2673-7275ShivajiPanditPost Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, Dist. Ahmednagar-413713 (MS), IndiaJournal Article20240203(Diacetoxyiodo)benzene has been used as an efficient catalyst for an improved and rapid one-pot synthesis of biscoumarin derivatives in excellent yield under reflux condition using water as a environmentally benign reaction medium. This aqua mediated Knoevenagel condensation of various aromatic and hetero-aromatic aldehydes with 4-hydroxycoumarin using catalytic amount of (diacetoxyiodo)benzene devoid the route of expensive, corrosive reagents and toxic solvents. Along with the routine aldehydes, the aldehydes like aryl-sulphonyloxybenzaldehyde, aryl-carbonyloxybenzaldehyde also leads to the product under the reaction conditions. High yields, shorter reaction times, one pot condensation, operational simplicity, easy work-up, purification of products by non-chromatographic methods are some additional features of this method.Iranian Journal of Catalysis (IJC)Multi-component preparation of diethyl/methyl 1,3-diaryl-1,2,3,6-tetrahydro-pyrimidine-4,5-dicarboxylates using hydrated phosphomolybdic acid as an efficient catalystVolume 5 (2015)Issue 2, June 201520240203Multi-component preparation of diethyl/methyl 1,3-diaryl-1,2,3,6-tetrahydro-pyrimidine-4,5-dicarboxylates using hydrated phosphomolybdic acid as an efficient catalystENMehdiAbaszadehPharmaceutics Research Center, Kerman University of Medical Sciences, Kerman 76175-493, Iran.MohammadSeifiDepartment of Chemistry, Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran; P.O. Box: 517MajidGhashangDepartment of Chemistry, Najafabad Branch, Islamic Azad University, P.O. Box: 517; Najafabad, IranJournal Article20240203The synthesis of diethyl/methyl 1,3-diaryl-1,2,3,6-tetrahydro-pyrimidine-4,5-dicarboxylates can be achieved using one-pot reaction from dialkylacetylene dicarboxylate, amines, and formaldehyde by employing hydrated phosphomolybdic acid (H3[P(Mo3O10)4].xH2O) as catalyst at room temperature. The effect of various solvent and catalyst amount was investigated. The salient features of the present method are: simple and straightforward work-up, cost-effective and environmentally benign procedure. The obtained yield of products was in the range of 75-92%. Based on the obtained results, the steric effects of the substituents in dialkylacetylene dicarboxylates played significant role in the rate of the reaction. When diethylacetylene dicarboxylate were used in this process, the corresponding product was obtained in good yields but in longer reaction time. Electron donating group on the amine was able to facilitate the transformation by giving evidently shorter reaction times.Iranian Journal of Catalysis (IJC)Highly efficient multicomponent Biginelli’s synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by Al-MCM-41 under solvent-free conditionsVolume 5 (2015)Issue 2, June 201520240203Highly efficient multicomponent Biginelli’s synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by Al-MCM-41 under solvent-free conditionsENSoheilSayyahiDepartment of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran.MehdiBehvandi BehvandiDepartment of Chemistry, College of Chemical Engineering, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran.Journal Article20240203In this study, an efficient and green process for the synthesis of dihydropyrimidin-2(1H)-ones from aromatic benzaldehydes, ethyl acetoacetate and urea using Al-MCM-41 as heterogeneous catalyst and microreactor under solvent-free conditions has been developed. The advantages of this method are easy work-up procedure, regeneration of the catalyst, clean and neutral reaction conditions.Iranian Journal of Catalysis (IJC)Phospho sulfonic acid: an efficient solid acid catalyst for the facile preparation of 1,4-dihydropyridinesVolume 5 (2015)Issue 2, June 201520240203Phospho sulfonic acid: an efficient solid acid catalyst for the facile preparation of 1,4-dihydropyridinesENSimaAbbaspourDepartment of Chemistry, Faculty of science, Islamic Azad University, Rasht Branch, Rasht, Iran.0000-0001-8940-2927ParisaJavanmardiChemistry Department, Qaemshahr Branch, Islamic Azad University, Qaemshahr, I. R. IranJournal Article20240203A simple and mild one-pot three-component reaction for the preparation 1,4-dihydropyridines has been developed from various aldehyde substrates, 1,3-dicarbonyl compounds (dimedone) and ammonium acetate (Hantzsch method) in the presence of a catalytic amount of phospho sulfonic acid (PSA) as an efficient and heterogeneous solid acid in EtOH at room temperature. Preparation of PSA is straightforward and handling of the reagent is also easy. The attractive features of this protocol are: (i) The elimination of corrosive liquid acids; (ii) the use of an inexpensive and relatively non-toxic catalyst, and (iii) reusability of the catalyst.Iranian Journal of Catalysis (IJC)Kaolin-SO3H as an efficient catalyst for one-pot synthesis of 1,2,4,5-tetrasubstituted imidazolesVolume 5 (2015)Issue 2, June 201520240203Kaolin-SO3H as an efficient catalyst for one-pot synthesis of 1,2,4,5-tetrasubstituted imidazolesENBiBi Fatemeh MirjaliliDepartment of Chemistry, College of Science, Yazd University, Yazd, P.O. Box 89195-741, Iran0000-0002-6588-4041HamidrezaAkramiYoung Researcher and Elite Club, Yazd Branch, Islamic Azad University, Yazd, Islamic Republic of Iran.Journal Article20240203Kaolin-SO3H as a new solid acid is prepared via reaction of kaolin and chlorosulfonic acid. This natural based catalyst is very inexpensive and easy available. Imidazoles are an important class of heterocycles being the core fragment of different natural products and biological systems such as anti-allergic, anti-inflammatory, analgesic, antifungal, antimycotic, antibiotic, antiulcerative, antibacterial, antitumor and inhibitors of the p38 MAP kinase. A simple, highly versatile and efficient synthesis of 1,2,4,5-tetrasubstituted imidazoles is achieved using Kaolin-SO3H as a catalyst at moderate temperature under solvent free condition. The key advantages of this process are high yields with simple work-up using easy available inexpensive natural based catalyst.Iranian Journal of Catalysis (IJC)Optical and photocatalytic properties Undoped and Mn-doped ZnO nanoparticles synthesized by hydrothermal method: Effect of annealing temperatureVolume 5 (2015)Issue 2, June 201520240203Optical and photocatalytic properties Undoped and Mn-doped ZnO nanoparticles synthesized by hydrothermal method: Effect of annealing temperatureENMaryamBordbarDepartment of Chemistry, Faculty of Science, University of Qom, Qom, Iran.SeyedMohammad VaseghFaculty of Technical & Engineering, Islamic Azad University, Tehran South Branch, Tehran, Iran.SomayeJafariFaculty of Science, Payame Noor University, Qom, Iran.AliYeganeh FaalDepartment of Chemistry, Payame Noor University, Iran.Journal Article20240203Undoped and Mn-doped ZnO nanoparticles were successfully prepared by the hydrothermal method with different annealing temperature conditions. Structural, chemical and optical properties of the samples were studied by X-ray diffraction (XRD), Field Emission scanning electron microscopy (FESEM), UV-Vis spectrophotometry and Fourier transform infrared (FT-IR) spectroscopy. The phase purity was confirmed by X-ray powder diffraction (XRD) and XRD spectra showed that all the samples were hexagonal wurtzite structure and as the annealing temperature increases the material becomes less crystalline. In addition, the average crystal size was found to be 15-30 nm from SEM and XRD. It is seen that the optical band gap increases when the ZnO is doped with manganese and decreases when annealing temperature increases. The photoacatalytic activity of Undoped and Mn-doped ZnO nanoparticles was tested by the degradation of metyl orang (MO) under UV light and indicated that Mn-doped ZnO has higher photocatalytic activity relative to ZnO nanoparticles and photocatalytic activity decreases when annealing temperature increases.Iranian Journal of Catalysis (IJC)Green synthesis of bis(indolyl)methanes in water using sulfonic acid functionalized silica (SiO2-Pr-SO3H)Volume 5 (2015)Issue 2, June 201520240203Green synthesis of bis(indolyl)methanes in water using sulfonic acid functionalized silica (SiO2-Pr-SO3H)ENZohrehKheilkordiDepartment of Chemistry, Alzahra University, Vanak Square, P.O. Box 1993893973, Tehran, Iran.ZeinabAslaniDepartment of Chemistry, Alzahra University, Vanak Square, P.O. Box 1993891176, Tehran, Iran.ShimaAsadiDepartment of Chemistry, Alzahra University, Vanak Square, P.O. Box 1993891176, Tehran, Iran.Journal Article20240203Bis(indolyl)methanes are important group of bioactive metabolites of terrestrial and marine regions. They were synthesized by different methods. Herein, a clean, one-pot synthesis of bis(indolyl)methane derivatives by cyclo-condensation reaction of indole and various aldehydes using Sulfonic acid functionalized silica (SiO2-Pr-SO3H) in aqueous media is reported. The advantages of this new method were simple operation, good yields, short reaction times and easy work-up. Sulfonic acid functionalized silica as an efficient heterogeneous solid acid catalyst could be prepared by simple operation from commercially available cheap starting materials such as silica. It catalyzes various organic reactions and could be easily removed, recovered and reused without significant loss of activity.Iranian Journal of Catalysis (IJC)L-Proline catalyzed synthesis of Betti bases and biscoumarin derivativesVolume 5 (2015)Issue 2, June 201520240203L-Proline catalyzed synthesis of Betti bases and biscoumarin derivativesENSamanehZahiriDepartment of Chemistry, Rasht Branch, Islamic Azad University, Rasht, IranMasoudMokhtaryDepartment of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran0000-0003-3763-7139MogharabTorabiDepartment of Chemistry, Rasht Branch, Islamic Azad University, Rasht, IranJournal Article20240203The direct three component modified Mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate Betti bases has been carried out over L-proline (20 mol%) with high efficiency under solvent free conditions at 70 OC. Also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of L-proline (20 mol%) in the ethanol under reflux conditions, lead to biscoumarin derivatives