Iranian Journal of Catalysis (IJC) Melamine trisulfonic acid as an efficient and reusable catalyst for the crossed-Aldol condensation of ketones and aldehydes under solvent-free conditions Volume 2 (2012) Issue 4, December 2012 2024 02 03 Melamine trisulfonic acid as an efficient and reusable catalyst for the crossed-Aldol condensation of ketones and aldehydes under solvent-free conditions EN Farhad Shirini Department of Chemistry, College of Science, University of Guilan, Rasht, Iran 0000-0002-7204-5000 Somayeh Sarvi Beigbaghlou Department of Chemistry, College of Science, University of Guilan, Rasht, I.R. Iran. Seyyed Vahid Atghia Department of Chemistry, College of Science, University of Guilan, Rasht, I.R. Iran. Journal Article 2024 02 03 Various types of aldehydes undergo crossed-Aldol condensation with ketones in the presence of melamine trisulfonic acid (MTSA) under solvent-free conditions. The reported method is mild, efficient and has the advantages such as using heterogeneous catalysis, short reaction times, high yields of the products and the recyclability of the catalyst.