Iranian Journal of Catalysis (IJC) ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction Volume 4 (2014) Issue 4, December 2014 2024 02 03 ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction EN Javad Safaei-Ghomi Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, I. R. Iran 0000-0002-9837-4478 Hossein Shahbazi-Alavi Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167 Kashan, I. R. Iran. Mohammad Reza Saberi-Moghadam Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran. Abolfazl Ziarati School of Chemistry, College of Science, University of Tehran, Tehran 14155-6455, Iran. Journal Article 2024 02 03 ZrP2O7 nanoparticles (NPs) as an efficient catalyst have been used for the preparation of 1,6-diamino-2- oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via one-pot coupling of hyrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes under reflux conditions in ethanol. Using this method we obtained low reaction times, easy isolation of the targeted molecules, excellent yields.