Iranian Journal of Catalysis (IJC) (Diacetoxyiodo)benzene (DIB) catalyzed green and efficient synthesis of biscoumarin derivatives in aqueous media Volume 5 (2015) Issue 2, June 2015 2024 02 03 (Diacetoxyiodo)benzene (DIB) catalyzed green and efficient synthesis of biscoumarin derivatives in aqueous media EN Amit Waghmare Post Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, Dist. Ahmednagar-413713 (MS), India 0000-0003-2673-7275 Shivaji Pandit Post Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, Dist. Ahmednagar-413713 (MS), India Journal Article 2024 02 03 (Diacetoxyiodo)benzene has been used as an efficient catalyst for an improved and rapid one-pot synthesis of biscoumarin derivatives in excellent yield under reflux condition using water as a environmentally benign reaction medium. This aqua mediated Knoevenagel condensation of various aromatic and hetero-aromatic aldehydes with 4-hydroxycoumarin using catalytic amount of (diacetoxyiodo)benzene devoid the route of expensive, corrosive reagents and toxic solvents. Along with the routine aldehydes, the aldehydes like aryl-sulphonyloxybenzaldehyde, aryl-carbonyloxybenzaldehyde also leads to the product under the reaction conditions. High yields, shorter reaction times, one pot condensation, operational simplicity, easy work-up, purification of products by non-chromatographic methods are some additional features of this method.