OICC PRESS Quantitative Analysis of β-Blockers in Water Samples by HPLC Using Directly Suspended Droplet Microextraction Volume 12 (2021) IJIC Issue 2, August 2021 2023 10 03 Quantitative Analysis of β-Blockers in Water Samples by HPLC Using Directly Suspended Droplet Microextraction 10.47176/IJIC.12.2.1 EN Mohammad Reza Abedi Department of Applied Chemistry, Quchan Branch, Islamic Azad University, Quchan, Iran 0000-0002-1262-4414 Journal Article 2023 10 03 The aim of this study is using Directly Suspended Droplet Microextraction (DSDME) as the sensitive drug assays in environmental waters. This work explains the success of this liquid-phase microextraction technique used as sample pre-concentration technique. This attractive method, which is selective and enable substantial pre-concentration, has been used for determination of three β-blockers; Atenolol, Metoprolol and Propranolol as the model compounds. The effective parameters such as organic solvent, pH of donor and acceptor phases, phase volumes, extraction and back-extraction time, stirring rate and addition of salt are discussed. The extracted β-blockers were analyzed at room temperature by High Performance Liquid Chromatography (HPLC), equipped an Agilent Eclipse XDB-C18 column with particle size of 5μm (250mm×4.6 mm i.d.) and programmed wavelength fluorescence detector. The mobile phase was 0.01molL-1 NaH2PO4 (adjusted to pH 3.0 with phosphoric acid)-methanol-acetonitril (45:45:10, v:v:v). The flow rate was 1.0 mLmin-1. The separated β-blockers were detected using fluorometric detection. The results showed that practical pre-concentration factors varied from 34.8 to 171.6.

OICC PRESS Mn(II) complex based 3-hydroxynaphthoic acid: A recyclable catalyst in synthesis of novel quinoline-5-one derivatives Volume 12 (2021) IJIC Issue 2, August 2021 2023 10 03 Mn(II) complex based 3-hydroxynaphthoic acid: A recyclable catalyst in synthesis of novel quinoline-5-one derivatives 10.47176/IJIC.12.2.2 EN Sadegh Allameh Department of Chemistry, Faculty of Science, Islamic Azad University, Mashhad, Iran. Mohammad Shaker Department of Chemistry, Faculty of science, Islamic Azad University, Mashhad, Iran. Azadeh Habibnia Milani Department of Chemistry, Faculty of Science, Islamic Azad University, Mashhad, Iran. Journal Article 2023 10 03 Mn(II) complex based on 3-hydroxy naphthoic acid is a new, recyclable and efficient catalyst for the synthesis of quinoline derivatives by the Hantzsch reaction. The one-pot four-component cyclocondensation of dimedone, aromatic aldehydes, acetophenone and ammonium acetate was carried under the conditions of refluxing in DMF at 110ºC. This method offers several advantages such as easy separation of catalyst, environmentally benign, mild reaction conditions and excellent of yields. In recent years, much attention has been focused on the application of heterogeneous reusable catalysts in organic synthesis because easy work-up, easy filtration and minimization of cost and waste generation. However, In view of the importance of quinoline derivatives, many classical methods for their synthesis were reported. The classical method involves an one-pot four-component condensation of dimedone, aldehydes, ethyl acetoacetate or similar compounds and ammonium acetate using of various catalysts such as montmorillonite, HClO4/SiO2, ionic liquids, Yb(OTf)3, nickel nanoparticles, Cu(II) complex and microwave.

OICC PRESS Evaluation of Anti-inflammatory Properties of Extracts of Sugar Beet (fruit and leaves), Beetroot (fruit and leaves), Pomegranate peel and Hyssop Volume 12 (2021) IJIC Issue 2, August 2021 2023 10 03 Evaluation of Anti-inflammatory Properties of Extracts of Sugar Beet (fruit and leaves), Beetroot (fruit and leaves), Pomegranate peel and Hyssop 10.47176/IJIC.12.2.3 EN Susan Khosroyar Department of Chemical Engineering, Quchan Branch, Islamic Azad University, Quchan, Iran Nadiya Sahebjamee Department of Chemical Engineering, Quchan Branch, Islamic Azad University, Quchan, Iran Farzad Kaj Department of Agriculture and Environmental Engineering, Rostock University, Rostock, Deutschland, Germany Journal Article 2023 10 03 Modern medicine, with all its great advances and having enough tools and equipment, is still unable to fully treat many diseases. Along with new medicine, there have always been traditional treatments with effective and practical instructions. The purpose of this research is to evaluate the anti-inflammatory properties of aqueous extracts and alcoholic extracts of hyssop, pomegranate peel, sugar beet, beetroot, and their leaves using the test of preventing denaturation of bovine serum albumin protein at 51 °C and comparing them. The extracts were prepared by the soaking method. The results showed that all tested species have anti-inflammatory effects. The anti-inflammatory property depends on the concentration of the extracts and their anti-inflammatory property increases with the increase in the concentration of the extracts. The anti-inflammatory effect of aqueous extracts is more than the anti-inflammatory effect of alcoholic extracts. According to the results, the hyssop plant (98.63%) has the highest anti-inflammatory properties, followed by beetroot leaves (87.67%) and sugar (83.11%).