OICC PRESS Nanopsychiatry: Engineering of nanoassisted drug delivery systems to formulate antidepressants Volume 13 (2022) Issue 3 2023 01 05 Nanopsychiatry: Engineering of nanoassisted drug delivery systems to formulate antidepressants 10.22034/ijnd.2022.1955783.2133 EN Karthick Harini Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai-603 103, INDIA. 0000-0002-8538-2049 Koyeli Girigoswami Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai-603 103, INDIA. 0000-0003-1554-5241 Agnishwar Girigoswami Medical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai-603 103, INDIA. 0000-0003-0475-2544 Journal Article 2023 01 05 ‌ ­Psychiatry involves the study of behavior, mind, personality, emotions, and human thoughts, which helps in the assessment and treatment of various mental health issues. Recently, the complexity of psychiatry has increased among all other medical specialties. Major depression is considered to become the global cause of disability by 2030. Antidepressants are the primary care or treatment given to any patient. Generally, antidepressants work by balancing the neurotransmitters in the brain, which accounts for the change in mood and emotions. The major problem limiting the use and research of antidepressants is blood brain barrier (BBB). They are highly selective for the movement of ions and molecules between blood and the brain. In particular circumstances, BBB hinders the entry of these drugs to the brain, thereby decreasing the efficacy, in turn increasing the side effects. Drug molecules larger than the pore size of BBB cannot pass through them. Nanopsychiatry deals with the application of nanoparticles in designing drugs, treatments, and diagnostic tools for several neurological and psychiatric illnesses. Nanoparticles exhibit a large surface-to-volume ratio which empowers them to remain a primary part of an effective drug delivery system. Nanocarriers made up of biodegradable polymers can overcome the limitations of BBB. Other than polymers, novel surfactant-based nanocarriers are a successful carrier of the drug across the BBB. This review discusses the severity of depression and the need for novel nanoassisted drug delivery systems.

OICC PRESS Surface, structural and optical investigation on Poly Vinyl Alcohol (PVA)/Bi2WO6 nanocomposite films Volume 13 (2022) Issue 3 2023 01 05 Surface, structural and optical investigation on Poly Vinyl Alcohol (PVA)/Bi2WO6 nanocomposite films 10.22034/ijnd.2022.1946867.2109 EN Rashmi Saragur Nanjundaiah Department of Industrial Production and Engineering, The National Institute of Engineering, Mysore- 570 008, Karnataka, India. Chandrashekar Hosur Kumara Department of Industrial Production and Engineering, The National Institute of Engineering, Mysore- 570 008, Karnataka, India. Sangamesha Madanahalli Ankanathappa Department of Chemistry, The National Institute of Engineering, Mysore- 570 008, Karnataka, India. Journal Article 2023 01 05 Bismuth tungstate (Bi2WO6) emerged as one of the most capable chromogenic compounds among transition metal oxide having wide opto-electronic applications. It is an n-type semiconducting material having bandgap around ~2.7eV. Conversely, NanoComposite (NC) materials have been investigated in order to tailor the properties polymers and also to widen the applications. In this context Poly (vinyl alcohol)/ Bismuth tungstate (PVA/Bi2WO3) NC films were prepared with various weight ratio of Bi2WO6 content viz.0, 0.1, 0.2 0.4, and 0.8 wt%. The solution combustion method was employed to prepare Bi2WO6 nanoparticles (NPs). Subsequently, synergistic effect of polymer matrix and Bi2WO6 NPs is characterized and analysed to estimate the enhanced properties. The surface morphology of the NC’s films was explored by Scanning Electron Microscopy (SEM). Elemental analysis is carried out using EDAX. The formation of polymer NC and its microstructural properties were investigated by X-ray diffraction technique and it is revealed that there is formation of orthorhombic phase for Bi2WO6 NPs with an average size of 35nm. Interaction of NP and PVA is studied using FT-IR spectrometer. The optical constants were evaluated by UV-visible spectrometer and it was found that NC films bandgap energy varied from 5.4 eV to 2.85eV for direct and from 4.57eV to 2.38eV for indirect bandgap. It is anticipated that these unique organic–inorganic NC materials are the emerging functional materials in the field of opto-electronics.

OICC PRESS Sheet-like Iron Hydroxyl Phosphate as an effective flame retardant and smoke suppressant for Polyacrylonitrile Volume 13 (2022) Issue 3 2023 01 05 Sheet-like Iron Hydroxyl Phosphate as an effective flame retardant and smoke suppressant for Polyacrylonitrile 10.22034/ijnd.2022.1955889.2134 EN Taher Rahimi-Aghdam Department of Chemistry, Amirkabir University of Technology (Tehran Polytechnic), 15875-4413, Tehran, Iran. Zahra Shariatinia Department of Chemistry, Amirkabir University of Technology (Tehran Polytechnic), 15875-4413, Tehran, Iran. 0000-0001-8533-6563 Journal Article 2023 01 05 A novel, one-step, facile and low-cost strategy was successfully designed to synthesize iron hydroxyl phosphate (IP) nanosheets via solvothermal method using iron (II) sulfate heptahydrate, ethylene glycol, and phosphoric acid. Then, for the first time, the flame retardant and smoke suppressant properties of the IP were studied. The synthesized IP nanosheets were added into the polyacrylonitrile (PAN) matrix, by a solvent blending method, to prepare PAN/IP nanocomposite. The structure and morphology of the IP nanosheets were carefully characterized by X-ray diffraction (XRD), X-ray photoelectron spectrum (XPS), Fourier-transform infrared (FT-IR) spectroscopy, Raman spectroscopy, field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM). In addition, the thermal stability, flame retardancy and fire hazard of the PAN/IP nanocomposite were investigated by thermogravimetric analysis (TGA), cone calorimetry, and UL-94 vertical burning test. The PAN/IP nanocomposite exhibited significantly higher smoke suppression and flame retardancy capability as well as less fire hazards than those of the pure PAN. Moreover, incorporation of the IP into the PAN matrix increased the residual char. These improvements were attributed to the ability of the IP to contribute in formation of effective barrier char layer on the PAN, sheet-like morphology of the IP as well as catalytic activity of the IP in carbon monoxide (CO) oxidation.

OICC PRESS Experimental prediction of flow boiling heat transfer coefficient of Water and Copper Oxide nanofluid using ANNOVA technique Volume 13 (2022) Issue 3 2023 01 05 Experimental prediction of flow boiling heat transfer coefficient of Water and Copper Oxide nanofluid using ANNOVA technique 10.22034/ijnd.2022.1954899.2127 EN Nandan Dattatraya Hegde Department of Mechanical Engineering, National Institute of Technology Warangal, Warangal 506004, Telangana State, India. Kupireddi Kiran Kumar Department of Mechanical Engineering, National Institute of Technology Warangal, Warangal 506004, Telangana State, India. Sudi Venkata Sai Sudheer Department of Mechanical Engineering, Vishnu Institute of Technology, Bhimavaram, Andhra Pradesh 534202, India. Journal Article 2023 01 05 In the present work the flow boiling charecteristics of CuO/water nanofluid were studied experimentally and the statistical as well as regression analysis were conducted to asses the flow boiling heat transfer coefficient and the influencing parameters. For this, CuO/water nanofluid was prepared by two step procedure for the particle concentration of 0.001%, 0.005%, and 0.01 % respectively.  The experiments were conducted by varying the heat flux and mass flux ranging from of 50-200 kW/m2 and 380-955 kg/s-m2, respectively for water and CuO/water nanofluids. All the experiments were conducted for the same temperature of water at heater inlet.  A full factorial multi-level design approach was used to design the experiments by considering the heat flux, mass flux and particle concentration are key influence parameters. Results showed that the boiling heat transfer is increases with mass flux and heat flux for both water and nanofluids. Furthermore, increasing the nanoparticle concentration enhances the flow boiling heat transfer rate and lowers the wall temperature. It is observed that at a mass flux of 954.29 kg/s-m2, the maximum decrease in wall superheat is 18.66 % for 0.01% CuO/water nanofluid. From statistical analysis, it is noticed that the aforementioned factors were statistically significant. Furthermore, heat flux has a considerable influence on the boiling heat transfer coefficient, which is followed by mass flux and particle concentration.  The heat transfer coefficient was predicted using a simplified quadratic model, which was found to be in good agreement with the experimental results.

OICC PRESS Thermoelectric properties of zigzag single-walled Carbon nanotubes and zigzag single-walled Boron Nitride nanotubes (9, 0) Volume 13 (2022) Issue 3 2023 01 05 Thermoelectric properties of zigzag single-walled Carbon nanotubes and zigzag single-walled Boron Nitride nanotubes (9, 0) 10.22034/ijnd.2022.1951622.2118 EN Reza Sadeghi Department of Physics, Ayatollah Amoli Branch, Islamic Azad University, Amol 46351-43358, Iran. Mohammad Reza Niazian Department of Physics, Ayatollah Amoli Branch, Islamic Azad University, Amol 46351-43358, Iran. 0000-0002-9007-8527 Mojtaba Yaghobi Department of Physics, Ayatollah Amoli Branch, Islamic Azad University, Amol 46351-43358, Iran. Moammad Ali Ramzanpour Department of Physics, Ayatollah Amoli Branch, Islamic Azad University, Amol 46351-43358, Iran. Journal Article 2023 01 05 In this paper, the thermoelectric properties of zigzag single-walled carbon nanotubes (SWCNT) and zigzag single-walled boron nitride nanotubes (SWBNNT) are investigated. For this purpose, the chirality is considered as (9, 0). The characteristics are computed at three arbitrary temperatures of 200K, 300K, and 500K. Results show the Seebeck coefficient of zigzag SWCNT increases by increasing the temperature, while decreases for the zigzag SWBNNT. The peak of the Seebeck coefficient of the zigzag SWCNT at the temperatures of 200K, 300K, and 500K are , , and , respectively. The associated values of SWBNNT are, , and , respectively.Besides, it is observed that at the temperature of 200K, the Seebeck coefficient zigzag SWBNNT is about 88 times the value of zigzag SWCNT. Moreover, due to the Seebeck coefficient sign type in the Fermi energy range, both of the considered nanostructures are semiconductors and n-type. It is depicted that the electrical conductivity and total thermal conductance of SWCNT are larger than SWBNNT. Efficiency is an important parameter to characterize the thermoelectric properties of nanomaterials. Results show the figure-of-merit (ZT) value of SWBNNT is much better than that of SWCNT. Due to the contribution of phonons, the zigzag SWBNNT has larger Seebeck coefficient. The studies show that the maximum value of ZT of the zigzag SWBNNT at the temperatures of 200K, 300K and, 500K are larger than 0.0207, 0.0342 and, 0.0718, respectively. The results of this study can be useful in the design of nanoelectronic, and cooling systems.

OICC PRESS Preparation, the physicochemical assessment, and the cytotoxicity of Cisplatin-loaded mesoporous Silica nanoparticles against head and neck squamous cell carcinoma cell line Volume 13 (2022) Issue 3 2023 01 05 Preparation, the physicochemical assessment, and the cytotoxicity of Cisplatin-loaded mesoporous Silica nanoparticles against head and neck squamous cell carcinoma cell line 10.22034/ijnd.2022.1954488.2125 EN Simin Sharifi Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Elaheh Dalir Abdolahinia Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran. Solmaz Maleki Dizaj Department of Dental Biomaterials, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. Touraj Nejatian Eastman Dental Institute, Faculty of Medical Sciences, University College London, London, UK. Zahra Seydi Department of Dental Biomaterials, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. Maryam Kouhsoltani Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran Yashar Rezaei Department of Dental Biomaterials, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran Masumeh Mokhtarpour Department of Physical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran Journal Article 2023 01 05 The aim of this study was to prepare, the physicochemical assessment and the cytotoxicity testing of cisplatin-loaded mesoporous silica nanoparticles against head and neck squamous cell carcinoma cell line (HNSCC). Cisplatin-loaded mesoporous silica nanoparticles were prepared through the precipitation method. The prepared nanoparticles were evaluated by conventional methods in terms of physicochemical properties. The cytotoxic effect of the nanoparticles and the free cisplatin were assessed on the head and neck squamous carcinoma cell line. The results showed that the prepared nanoparticles with nanometer size and the negative surface charge belonged to the MCM-41 silica family. TEM images established the mesoporous construction and the rod-shaped morphology of the produced nanoparticles. Based on Brunauer-Emmett-Teller (BET) analysis, the specific surface area, pore volume, and pore diameter decreased compared to free mesoporous silica because of drug filling into the mesoporous pores. The nanoparticles showed a two stage release pattern that continued slowly until the 35th day. Mesoporous silica nanoparticles displayed no significant cytotoxic effect on HNSCC. Cisplatin displayed a cytotoxic effect with IC50 of 82.01 μM and 33.67 μM in 24 h and 48 h incubation times, respectively. However, cisplatin-loaded mesoporous silica nanoparticles displayed a cytotoxic effect with IC50 of 26.17 μM and 13.28 μM in 24 and 48 h incubation times, respectively. The results can highlight the capability of cisplatin-loaded mesoporous silica nanoparticles to be applied in the treatment of oral cancerous cells.

OICC PRESS Microwave-assisted greener synthesis of Silver nanoparticles using Entada rheedii leaf extract and investigation of its anticancer and antimicrobial properties Volume 13 (2022) Issue 3 2023 01 05 Microwave-assisted greener synthesis of Silver nanoparticles using Entada rheedii leaf extract and investigation of its anticancer and antimicrobial properties 10.22034/ijnd.2022.1952713.2126 EN Anjaly Mathew Department of Chemistry, Sree Neelakanta Government Sanskrit College, Pattambi, Kerala, India Analiparambil Ravindran Ramesh Department of Chemistry, Government Victoria College, Palakkad, Palakkad, Kerala, India Abdul Rasheed Vazhanthodi Department of Zoology, Sree Neelakanta Government Sanskrit College, Pattambi, Palakkad, Kerala, India Binitha Valiyaparmbil Sivadasan Department of Zoology, Sree Narayana College, Nattika, Thrissur, Kerala, India Sabira Ovungal Department of Zoology, Sree Neelakanta Government Sanskrit College, Pattambi, Palakkad, Kerala, India Sujith Madathilpadi Subrahmanian Department of Zoology, Sree Neelakanta Government Sanskrit College, Pattambi, Palakkad, Kerala, India Prasant Chittadimangalath Department of Zoology, Sree Neelakanta Government Sanskrit College, Pattambi, Palakkad, Kerala, India Anthyalam Parambil Ajaykumar Department of Zoology, Sree Neelakanta Government Sanskrit College, Pattambi, Palakkad, Kerala, India Journal Article 2023 01 05 In the current investigation phytochemically mediated, easy, efficient, and eco-friendly green synthesis of silver nanoparticles (AgNPs) was carried out using Entada rheedii leaf extract as a reducing and capping agent in a microwave-assisted synthetic pathway. UV-Visible spectroscopy, IR spectroscopy, scanning electron microscope (SEM), and transmission electron microscopic (TEM) techniques were used to confirm the formation of silver nanoparticles. The functional groups present in the capping agent were identified by FTIR analysis.  SEM and TEM analysis studied the surface morphology of the biosynthesized AgNPs. AgNPs also showed significant antibacterial effects against four different bacterial pathogens Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Vibrio cholera. Additionally, the prepared AgNPs exhibited solid anticancer activity against Dalton's lymphoma ascites (DLA) cells.

OICC PRESS Synthesis and characterization of Cobalt Oxide nanoparticles using Momordica charantia and its photocatalytic activity Volume 13 (2022) Issue 3 2023 01 05 Synthesis and characterization of Cobalt Oxide nanoparticles using Momordica charantia and its photocatalytic activity 10.22034/ijnd.2022.1956438.2137 EN Samuel Alwin David PG & Research Department of Chemistry, V. O. Chidambaram College, Tuticorin, India. Asirvatham Doss PG & Research Department of Botany, V. O. Chidambaram College, Tuticorin, India Rajamma Powel Praveen Pole PG & Research Department of Zoology, V. O. Chidambaram College, Tuticorin, India Thankappan Pushpabai Kumari Pushpa Rani Department of Microbiology, St. Mary’s College (Autonomous), Tuticorin, India Raveendran Padma Latha Reshmi Department of Biotechnology, Malankara Catholic College, Mariagiri Tamilnadu, India. Ramakrishnan Rajalakshmi PG & Research Department of Botany, V. O. Chidambaram College, Tuticorin, India. Journal Article 2023 01 05 Synthesizing plant-derived nanoparticles attract attention due to both their broad-spectrum biological applications and sustainable production. This paper describes the production of Cobalt oxide nanoparticles (Co3O4 NPs) using M. charantia leaf extract. The Uv–Vis absorption spectrum of them has peaks at 309 and 595nm. FTIR spectroscopy reveals bands at 580cm-1 and 667cm-1 and confirms the formation of Co3O4. The particle size was determined by XRD to be between 44.68 and 89.20nm. The Field Emission Scanning Electron Microscopy (FESEM) showed that Co3O4 NPs were irregular in shape and between 40 and 90nm in size. Further, the dye degrading capacity of this nanoparticle was ascertained. The dye degrading capacity of Co3O4 NPs exhibited was 81.50% obtained at 90 minutes of light irradiation.